Solve Pharmacology INICET 2020 1. A patient was treated with TCA for a major depressive episode in the hospital for 4 weeks. What is the main concern while considering his discharge from the hospital? Need for drug monitoring Suicidal risk ECG monitoring for arrhythmias Sedation is the side effect None 2. A boy presents with pallor and lymphadenopathy, the X-ray of his skull is given below. Which of the following drug is not used for the management of the suspected diagnosis? Cyclosporine Vinblastine Methotrexate Vincristine None 3. All of the following are the uses of enteric-coated drugs except: Prolongs the half-life of the drug Protect the gastric mucosa from the irritant effects of certain drugs Protect the acid labile drug from gastric acidity Deliver drugs distal to the stomach None 4. A patient who was on antiepileptics for the management of seizure disorder started having visual disturbance. Evaluation reveals the contraction of the visual field. Is the drug responsible is likely to be? Ethosuximide Phenobarbitone Vigabatrin Levetiracetam None 5. Which of the following statements is correct for a patient on high dose of penicillin and gentamicin? TDM is done with penicillin because of narrow therapeutic index TDM is done with both because of dangerous side effects TDM is done with gentamicin because of narrow therapeutic index Both drugs do not need monitoring None 6. What is the most common drawback of the given device? Does not provide multiple doses Bacterial contamination Drug deposition in the oropharynx Not portable None 7. If a patient who is on metoprolol is started on verapamil, which of the following side effects would be seen? Tachycardia Ventricular fibrillation Torsades de pointes Bradycardia with AV block None 8. A known asthmatic patient with fever and sore throat was prescribed an antibiotic. Two days later he presents with a maculopapular rash. Which of the following drugs might have caused this? Fexofenadine Salbutamol Prednisolone Amoxicillin None 9. The response on stimulation of muscarinic receptor is: Ejaculation Erection Increased myocardial contractility Bronchodilation None 10. Which of the following drugs promotes bone formation? Raloxifene Calcitonin Teriparatide Bisphosphonates None 11. Which of the following statements is true about disulfiram? When used with alcohol, the patients feels drowsy, with chest discomfort and respiratory depression It can be initiated even in minimally motivated persons Its action persists up to 2-3 days after stopping the drug It is an anti-craving drug None 12. Rosuvastatin should not be combined with which of the following drugs? Oxycodon Clarithromycin Rivoraxaban Adalimumab None 13. Which of the following antidepressants causes the least sexual dysfunction? Mirtazapine Venlafaxine Fluoxetine Imipramine None 14. Which of the following is not a prodrug? Primidone Proguanil Fluorouracil Sulindac None 15. A patient presented with pelvic fracture and head trauma after a road traffic accident. He was given IV morphine for pain relief following which he developed respiratory difficulty. What could be the most likely cause? Pelvic Fracture Cerebral Edema Pulmonary embolism CO2 retention due to opioid use None 16. An elderly woman on treatment for migraine presents with chest pain. She has a previous history of angina/MI. Which of the following mechanism of the prescribed drug for migraine might have caused this presentation? 5-HT antagonist 5-HT agonist Nitric oxide-mediated vasodilation Calcium Channel Blocker action None 17. Which of the following topical antifungal has both anti-inflammatory effects and anti-pruritic action? Terbinafine Sertaconazole Ketoconazole Luliconazole None 18. The normality of 2M HCI is 1M H2SO4. Half Same Twice 4 times None 19. If codeine is coming to the market in combination with dextromethorphan as an anti-tussive, this combination Should not be used due to risk of addiction Can be used as both have different mechanism of action Can be used to treat cough effectively Should not be used as it is irrational None 20. A patient is started on lithium therapy. Which of the following side effects should the patient be asked to watch out for to monitor for toxicity? Vertigo and Diarrhoea Malaise and sore throat Breathlessness Fever None 21. Which of the following is least likely to be useful in a patient with severe COVID-19? Favipiravir Oxygen Low molecular weight heparin Steroids None 22. The antidote for fibrinolytic therapy is? EACA Alteptase Dalteparin Tranexamic acid None 23. A psychiatric patient was started on lithium for the management of bipolar disorder. To monitor the blood lithium levels, at what time interval should the blood sample be collected after the administration of lithium tablets? After 12 hours After 24 hours Immediately after taking tablets After 6 hours None 24. Which of the following drugs do not need dose adjustment in renal failure? Saxagliptin Sitagliptin Linagliptin Vildagliptin None 25. Which of the following is a second-line anti-tubercular drug? Acyclovir Streptomycin Ethionamide Vancomycin None 26. Which of the following anti-tubercular drug is not bactericidal? Rifapentin Isoniazid Thioacetazone Kanamycin None 27. Which of the following drugs exacerbates myasthenia and is usually avoided in a patient with myasthenia gravis? Meropenem Digene Phenytoin Lidocaine 2,4 1,2 1,4 1 None 28. Which of the following drugs are used for absence seizures? Valproate Carbamazepine Gabapentin Ethosuximide 1,2, & 3 2 & 3 1 & 4 1,2,3, & 4 None 29. Match the following dilution of adrenaline and its use: A) 1:1000 B) 1:10000 C) 1:10000 Cardiac arrest Anaphylaxis Local anesthesia A-2 B-1 C-3 A-1 B-2 C-3 A-1 B-3 C-2 A-3 B-2 C-1 None 30. Which of the following is correct about the drugs used in Gout? Aspirin is not used as it decreases the uric acid excretion Diclofenac is used as it concentrates in the joint Indomethacin is used as it acts by multiple pathways Aspirin is used as it is the most powerful NSAID 1, 2, 3, 4 1, 2, 3 1, 2 3, 4 None 31. Match the following bacteria with the drug of choice used for each. A. BacteroidesB. MRSAC. HemophilusD. Klebsiella Vancomycin Metronidazole Meropenem Penicillin A-4, B-1, C-2, D-3 A-3, B-4, C-1, D-2 A-1, B-3, C-4, D-2 A-2, B-1, C-4, D-3 None 32. Which of the following statements is true? Morphine used in pulmonary edema Pethidine used in biliary colic Indomethacin is used in headaches. Aspirin used in peptic ulcer disease 1, 2, 3 1, 3 2, 3, 4 1, 4 None 33. Which of the following drug reduces mortality in COVID-19 patients? Dexamethasone Remdesivir Favipravir 1, 2 2, 4 1 1, 2, 3 None 1 out of 33 Time's up
