Solve Pathology AIIMS 2018 1. A patient working in a factory presented with lung fibrosis and thickening of pleura. Biopsy was done. Diagnosis from the histopathology picture is: Asbestosis Silicosis Tuberculosis Mesothelioma None 2. Which of the following is a true statement about apoptosis? Karyolysis is present There is enzymatic digestion of cellular contents It is associated with adjacent inflammation Plasma membrane remains intact None 3. All leukemias come under provisional entity in WHO 2016 classification of hematolymphoid tumors except B-lymphoblastic leukemia/lymphoma with hypodiploidy Acute myeloid leukemia with RUNX1 mutation Splenic B-cell lymphoma/leukemia Natual Killer cell lymphoblastic leukemia/lymphoma None 4. Which of the following is the color of vacutainer containing sodium fluoride as a content? Blue Grey Red Yellow None 5. A 62-year-old HIV-positive man presented with fever and breathlessness for 2 weeks. Imaging shows dense infiltration in the lower lobe and the lung biopsy showed the following finding. What is the diagnosis? CMV-associated organizing pneumonia Cryptococcal pneumonia Small-cell lung cancer Tuberculosis None 6. What does the following image show? Amoebic autophagy Emperipolesis Phagocytosis Autophagy None 7. A patient presents with abdominal distension and intermittent fever. Peripheral smear findings are normal. A tumor is resected and the histopathology image of the resected lymph node is shown below. What is the most probable diagnosis? Angiolymphoma Hodgkin's lymphoma Castleman disease IgG4-related disease None 8. Choose the correct option regarding the storage temperatures of blood components RBC 20-22°C, Platelet 2-6°C, FFP -30°C RBC 2-6°C,Platelet 20-22°C, FFP -30°C RBC -30°C, FFP 2-6°C, Platelet 20-22°C RBC 20-22°C, FFP below -30°C, Platelet 2-6 °C None 9. Which of the following is not usually involved in the immunohistochemistry of acute lymphoblastic leukemia? CD1a CD3 Cytokeratin Tdt None 10. Antibody-dependent cellular cytotoxicity (ADCC) is seen with: Natural killer (NK) cells only Macrophages only Neutrophils and eosinophils only NK cells, neutrophils and eosinophils None 11. Acid mucin is stained by. Masson trichrome Alcian blue PAS (Periodic Acid Schiff) PTAH(Phosphotungstic Acid Hematoxylin) None 12. A middle-aged male patient has proteinuria. Looking at the immunofluorescence image below, what is the diagnosis? Post-streptococcal glomerulonephritis (PSGN) Focal segmental glomerulosclerosis (FSGS) Good pasture syndrome Lupus nephritis None 13. Which of the following is involved in the recognition and clearance of necrotic cells? Toll-like receptors (TLRs) Inflammasome Manoreceptor P selectin None 14. Toluidine blue staining is used in the Identification of which of the following cells? Macrophage Lymphocyte Fibroblast Mast Cell None 15. A patient has been brought with severe bleeding to your ER. His blood group is unknown. Fresh frozen plasma from which of the following blood groups can be given? O AB A B None 16. t(11,22) is best diagnosed by Bone marrow aspiration FISH (Fluorescence in-situ hybridization) Next-generation sequencing Conventional karyotyping None 17. Which of the following proto-oncogenes is not implicated in carcinoma of the thyroid? RAS BRAF RET p53 None 18. NARP syndrome is a? Lysosomal storage disorder Golgi body transport disorder Mitochondrial function disorder Glycogen storage disorder None 19. Gamma delta T cell (TCRs) receptors recognize Lipids without MHC proteins Peptides with MHC proteins CD3 CD20 None 20. Which of the following is true about Turner's syndrome? Absence of neck webbing is associated with higher risk of co-arctation of aorta Noonan syndrome is more associated with cardiac defects Webbing of hands and toes is associated with risk of visceral anomalies Webbing of neck is associated with higher risk of cardiac anomalies None 21. Cancer that least commonly spreads by lymphatic route is Merkel Cell Carcinoma Squamous cell carcinoma Basal Cell Carcinoma Malignant melanoma None 22. What is correct regarding the transfusion of the blood received from the blood bank? It should be completed within 6 hours of receiving from the blood bank. It should be completed within 4 hours of receiving from the blood bank. It should be started within 4 hours of receiving it from the blood bank. No such time restraint and can be done anytime. None 1 out of 22 Time's up
