biochemisrtry pYQ 2018 NEET-PG 2018 Solve Biochemistry NEET-PG 2018 Total Questions: 16 1. Vanillyl mandelic acid is excreted in urine in which of the following conditions? Alkaptonuria Pheochromocytoma Diabetic ketoacidosis Carcinoid syndrome None 2. Which of the following is responsible for the negative charge in fibrinopeptide A? Histidine and Lysine Glutamate and Valine Aspartate and glutamate Serine and Threonine None 3. Which of the following statements is true about vitamin K? It is a water soluble vitamin. Deficiency of vitamin K leads to hypercoagulability Menaquinone is the dietary source of vitamin K found in green vegetables. Prolonged use of antibiotics leads to vitamin K deficiency. None 4. Serotonin is also known as? 5 hydroxytryptamine 5 hydroxytryptophan 5 carboxytryptamine 5 carboxytryptophan None 5. What do chaperones assist in? Protein modification Ubiquitinization of proteins Protein cleavage Protein folding None 6. Defective fumarylacetoacetate hydrolase enzyme is associated with Type 2 Tyrosinemia Type 1 Tyrosinemia Type 4 Tyrosinemia Type 3 Tyrosinemia None 7. Which of the following is true about DNA polymerase I? It is found in prokaryotes. It is involved in the creation of okazaki fragments. It is the primary enzyme of DNA synthesis. It synthesises RNA primers. None 8. A newborn baby refuses breast milk since the 2nd day of birth but accepts glucose water. He develops vomiting and severe jaundice by the 5th day. Benedict's test was positive for urine and blood glucose was low. The most likely cause is due to the deficiency of Galactokinase Aldose reductase UDP galactose-4-epimerase Galactose-1-phosphate uridyl transferase None 9. A patient presents with recurrent kidney stones. The microscopic examination of the urine specimen is shown below. Which of the following is not seen in the urine of this patient? Lysine Arginine Cysteine Cystine None 10. In which condition is excessive urinary excretion of 5-hydroxy indole acetic acid seen? Albinism Alkaptonuria Phenylketonuria Carcinoid syndrome None 11. A 45-year-old woman with hypertriglyceridemia is considered for niacin therapy. She is a known diabetic managed adequately with sugars well under control. Why should niacin be used cautiously in this patient? It can cause scleroderma which makes injecting insulin difficult. It can cause hyperglycemia. It can cause hypoglycemia. It can increase the metabolism of oral hypoglyemic drugs. None 12. Which of the following should be avoided by a patient of fish odour syndrome? Choline Biotin Pantothenic acid Niacin None 13. Which of the following can alter the gene expression by methylation and acetylation but not change the gene sequence? Epigenetics Mutation Inversion Translocation None 14. Which of the following is true regarding an allosteric modifier? Desaturates the enzyme Binds to the cataytic site Causes the enzyme to work faster only. Participates in feedback regulation None 15. The flipped LDH ratio implies LDH 2 > LDH 1 LDH 1 > LDH 2 LDH 2 > LDH 3 LDH 3 > LDH 2 None 16. Which of the following is the most common end-product of fatty acid synthesis pathway? Oleic acid Arachidonic acid Palmitic acid Acetyl CoA None Time's up
