Solve Biochemistry INICET 2020 1. A TPN bag consists of 100g glucose, 30g amino acids, and 40g lipids. What is the amount of calories provided? 640 KCal 680 KCal 840 KCal 880 KCal None 2. The enzyme that is common for both glycolysis and gluconeogenesis is? Phosphoglycerate kinase Phosphofructokinase Pyruvate kinase Phosphoenolpyruvate carboxykinase None 3. The given chemical structure is of: Chondroitin sulfate Heparin Keratan sulfate Dermatan sulfate None 4. The correct order of steps in Polymerase Chain Reaction (PCR) is Denaturation, Annealing, Extension Hybridisation, Annealing, Elongation, Denaturation Elongation, Denaturation, Hybridisation, Annealing Annealing, Extension, Denaturation None 5. What is true about the Hayflick limit? Telomerase activity is unrestricted Human cells can divide a finite number of times only RNA polymerase can function for. a finite number of times only Free radical oxidation level is unrestricted None 6. Which of the following is not a true statement regarding telomerase? Present only in Eukaryotes Has reverse transcriptase activity Maintain the chromosome length Involved in DNA Repair None 7. Gibbs free energy curve of an enzyme-catalyzed reaction is given by A B C D None 8. Ammonia in the brain is detoxified to form Glutamine Urea Alanine Ammonium ions None 9. The maximum thermic effect is seen with a meal that has Carbohydrates Fat Protein Mixed meal having all 3 in equal amount None 10. The sequence of vitamin D synthesis is? Skin- Liver- Kidney Liver- Skin- Kidney Skin- Kidney- Liver Liver- Kidney- Skin None 11. DNA Methylation is not involved in? RNA Splicing Chromatin remodelling Base pair excision Gene Silencing None 12. Which of the following enzymes has the highest catalytic efficiency? Km of an enzyme = 2 micromole and Kcat = 200 per sec Km of an enzyme = 2000 nanomole and Kcat = 50 per sec Km of an enzyme = 10 micromole and Kcat = 20 per sec Km of an enzyme = 4 micromole and Kcat = 200 per sec None 13. Glucose is stored in the form of glycogen because, It can provide glucose for about 1 week when needed It can be stored at multiple organs It is compact It has multiple reducing ends None 14. Which of the following are vitamin-B12 dependent enzymes? Methionine synthase Homocysteine synthase Folate reductase Methyl malonyl CoA isomerase 1,4 1,2,3,4 1,3 1,2,3 None 15. Which of the following enzymes are involved in gluconeogenesis? Phosphoenol pyruvate kinase Hexokinase Pyruvate carboxylase Pyruvate kinase Glucose 6 phosphatase 1,2,4,5 3,4 4,5 2,4 None 16. DNA methylation is not related to? Chromatin Remodelling Mismatch repair DNA replication Gene silencing None 17. Ketosis is common in type 1 DM due to: Decreased acetyl CoA in the TCA cycle Decreased beta-oxidation of fatty acids Increased beta-hydroxy butyryl synthase Increased mobilization of fat from the adipose cell 1,2,3,4 2,3 4 1,3,4 None 18. The enzyme that is not used in cholesterol synthesis? Thiolase HMG CoA reductase HMG COA lyase HMG COA synthase None 19. Dicoumarol inhibits the action of vitamin K by? Non-competitive inhibition Competitive inhibition Suicide inhibition Uncompetitive inhibition None 1 out of 19 Time's up