Solve Microbiology INICET 2020 1. Specimen handling for molecular testing of SARS-COV 2 would require BSL1 BSL2 BSL3 BSL4 None 2. Which of the following method is employed to measure the viral load? Western blot ELISA Real time PCR Immunoelectrophoresis None 3. A resident had a needle stick injury while dealing with Hepatitis B- patient. Serology was done and HBsAg was negative and the Anti-HBs was >105 mIU/ml. What is the next step of management? Immunoglobulin with full vaccination Repeat full course of vaccine Booster dose of vaccine No treatment required as he already has Hep B antibody titres from vaccination None 4. All of the following is true regarding scrub typhus except: Lymphadenopathy is a feature Transmitted by chiggers Man is an accidental host Produces NLF producing colonies in MacConkey agar None 5. The life cycle of an organism is given below. Identify the vector involved. Soft tick Hard tick Louse Trombiculid mite None 6. False about the Ebola virus is: Nosocomial transmission seen Bats acts as reservoir Transmitted by mosquito It is a filovirus None 7. What is the causative organism for the condition shown in the image below? Echinococcus granulosus Schistosoma mansoni Trypanosoma cruzi Schistoma japonicum None 8. Identify the condenser A B C D None 9. A young male presents to the STD clinic with painful lesions as shown in the image. What is the most likely microscopic finding of the lesion? Pund cells Tzank cells Guarnieri bodies Henderson-Patterson bodies None 10. The presence of antibodies against SARS COV 2 in the blood likely indicates Previous infection even if patient has been asymptomatic A high risk of reinfection Presence of acute viral load That the patient is in window period None 11. A patient has complains of fever with chills. A throat examination reveals swollen glands and a thick, whitish membrane over his tonsils. Albert staining is to be done. What are the constituents of Albert's stain? Carbol fuschin and methylene blue Carbol fuschin and malachite green Toluidine and methylene blue Toluidine blue 'O' and malachite green None 12. Which of the following is the enzyme conjugate in the given ELISA technique? A B C D None 13. Pneumonia due to a gram-negative pleomorphic bacillus growing on chocolate agar which is catalase and oxidase-positive is: Pseudomonas E.coli Haemophilus influenzae Actinomyces None 14. A 30-year-old male presented to the OPD with painful genital ulcers. Which of the following can cause a painful ulcer on the glans penis? Chlamydia Chancroid Syphilis Lymphogranuloma venereum None 15. A patient who underwent a renal transplant 3 months ago comes with complaints of diarrhea for the last 9 days. The stool sample was subject to Kinyoun stain revealing 4-6µm structures shown below. Which of the following is true about the organism? Pathogen does not shows autoinfection It is an obligate intracellular organism Cryptosporidium parvum is the most common organism implicated worldwide Oocysts are immediately infective after being excreted in the stool None 16. Which protein is present in the HPV vaccine? E6, E7 L1 E1, E2 L2 None 17. GeneXpert detects mutations in which of the following genes? rpoB KatG pncA inhA None 18. A patient presented with meningitis with a history of fever for 4 days and erythematous rashes on the chest. There was no history of travel and tick bite. His CSF findings showed increased protein, normal glucose, mild lymphocytosis and few RBCs. Which of the following is the most likely organism to cause this clinical picture? Meningococci Entero virus Strep pneumoniae West nile virus None 19. A patient presents with seizures. His CT head reveals multiple parenchymal cysts. Which of the following is correct regarding management in this case? Antiparasitic drugs followed by steroids Steroids before antiepileptics Steroids followed by antiparasitic drugs Continue antiepileptics None 20. A stool sample is collected. The specimen is processed for examination and is labeled at different levels as A, B, C, and D. Identify the level at which parasitic ova will be seen when viewed under a microscope. A B C D None 21. The transplacental transmission of the organism given in the image which causes microcephaly is- Zika virus Nipah CMV Rubella None 22. Type IV hypersensitivity is due to? Cell mediated response Cell mediated and antibody mediated response Antibody mediated response Innate response None 23. The disruption of which of the following is responsible for watery diarrhea in cholera caused by Vibrio? Macula densa Intercalated discs Hemidesmosomes Zonula occludens None 24. Affinity maturation is due to: Somatic hypermutation Isotype switching mRNA splicing VDJ rearrangement None 25. A child was brought to the OPD with a swollen, red knee joint that is tender to touch. 2 weeks prior, he had an episode of fever with bloody diarrhea. Which of the following could be the possible organism? Shigella Rotavirus Giardia E. coli None 26. A farmer presents with a swollen foot and multiple sinuses as shown in the below image. What is the most likely diagnosis? Squamous cell carcinoma Mycetoma Nocardia Sporotrichosis None 27. The given life cycle belongs to which of the following organisms? Leptospira Salmonella typhi Yersinia pestis Hanta virus None 28. Which of the following disease has the highest mortality once clinically manifested Rabies Ebola Nipah Zika None 29. A patient presents with a mobile, warm to touch nodule in the neck. On the anaerobic culture of the biopsy material from this swelling, it showed colonies as shown in the image which had gram-positive branching rods on staining. Which of the following is the drug of choice in this condition? Penicillin Cotrimoxazole Surgical Excision and Drainage Doxycycline None 30. Match the following E.coli with their respective pathogenesis.  A-4,B-2,C-3.D-1 A-1,B-3,C-2,D-4 A-4,B-3,C-2,D-1 A-1,B-2,C-3,D-4 None 31. Galactomannan in serum is seen in Mucormycosis Cryptococcosis Invasive aspergillosis Systemic candidiasis 1 & 2 2 3 & 4 4 None 32. Match the following parasites with their respective hosts: Parasite Host  A. Diphyllobothrium Sheep  B. Paragonimus Crayfish  C. Brugia Cyclops  D. Fasciola Mansonia  A-2, B-1,C-4,D-3 A-3, B-2, C-4, D-1 A-4, B-3, C-1, D-2 A-1, B-2, C-3, D-4 None 1 out of 32 Time's up
