Solve Microbiology INICET 2022 1. What is the ratio of T cells to B cells in a healthy adult? 1:1 1:2 1:3 3:1 None 2. A patient presents to you with left-sided flank pain. A CT scan was done which is shown below. Which of the following statements is incorrect regarding the condition? FNAC or biopsy to be done before nephrectomy A segmented dog tapeworm is the causative agent Cyst contents can produce anaphylactic reaction Albendazole can be started preoperatively None 3. A microbiologist stained a tissue sample and found thin, filamentous bacteria, which resembled Nocardia sp. What other staining technique should be done to confirm the presence of Nocardia? Ziehl-Neelsen staining Silver impregnation Albert stain Modified acid-fast stain None 4. Which virus can be identified by a PCR method and is endemic to India? Hendra virus West Nile virus Ebola virus Yellow fever None 5. What is the microscopy technique to produce high contrast image of transparent, live bacteria? Electron microscopy Dark field microscopy Phase contrast microscopy Polarized microscopy None 6. SARS-CoV-2 can be detected by all except Southern blotting Rapid antigen test to detect spike proteins Real-time PCR to detect viral mRNA ELISA to detect spike proteins None 7. Which of the following agents can be used as a disinfectant but not a sanitizer? Hydrogen peroxide Methyl paraben Bleaching powder Penicillin None 8. Which of the following has been reported to have endemic transmission in India? Yellow fever Crimean-Congo hemorrhagic fever Ebola Hendra virus None 9. Match the following.  A-4, B-1, C-2, D-3 A-4, B-2, C-3, D-1 A-2, B-1, C-3, D-4 A-4, B-1, C-3, D-2 None 10. A patient comes with a history of high fever for 5 days and altered sensorium. On further probing, it was found that he had two seizures one day ago. Peripheral smear shows the following findings. How will you manage this patient? Doxycycline 100 mg intravenously for 7 days Artesunate 2.4 mg/kg intravenously at 12 and 24 hours, followed by daily once Clindamycin 600 mg intravenously 8 hourly for 7 days Chloroquine intramuscularly 8 hourly for 3 days None 11. Vaccination against which of the following is recommended in the elderly? Measles Pneumococcal meningitis Rotavirus Varicella zoster virus 2, 4 1, 4 1, 2, 3 2, 3, 4 None 12. Which of the following are acid-fast staining organisms? Mycobacterium leprae Nocardia Actinomyces Isospora belli Cryptosporidium parvum 1,2,3,4 4,5 1,2,4,5 2,3 None 13. Vesicular rash is seen in Hand, foot, and mouth disease Zika fever Roseola infantum Dengue None 14. Delayed hypersensitivity is due to Interleukin-2 Interferon gamma Interleukin-4 Interleukin-12 None 15. Which of the following is wrong regarding primary and secondary immune response? 1 2 3 4 None 16. The cell wall depicted below is most likely to belong to which of the following organisms? Rhinosporidium seeber Aspergillus fumigatus Mycobacterium tuberculosis Mycoplasma pneumoniae None 17. Which of the following viruses show genetic change similar to influenza virus? 1 2 3 4 None 18. Which disease causes the lesion shown in the image below? Rocky mountain spotted fever COVID-19 Scrub typhus Malaria None 19. Which of the following is true about anti-CMV IgG antibodies? IgG avidity assay helps in differentiating past and primary infection Indicates acute CMV infection Denotes chronic CMV infection with immunity to other serotypes Denotes latent CMV infection None 20. Which of the following is an example of Mollicutes? Chlamydophila pneumoniae Ureaplasma urealyticum Orientia tsutsugamushi Chlamydia trachomatis None 21. Which of the following method of disinfection and sterilization can also kill spores? Ethylene Oxide Pasteurization Ortho-Phthalaldehyde Glutaraldehyde 1, 3 and 4 1, 2 and 4 2,3 and 4 1,2,3 and 4 None 22. The inclusion body Rickettsial morula is found in neutrophils during infection caused by: Rickettsia conorii Anaplasma phagocytophilum Ehrlichia chaffeensis Rickettsia rickettsii None 23. A forest worker developed skin lesions over the forearm, which initially started as macules but then became nodules. Histology of the nodules shows the following findings. Which of the following is true regarding this condition? Angioinvasion is common, especially in people with hemolytic anemia These bodies are formed by engulfment of the dead fungi by the macrophages. It is a dimorphic organism, and yeast forms are seen in clinical sample. The organism does not invade underlying fascia, tendon, muscle, or joints. None 24. A petechial rash is associated with all the following, except, Zika virus Roseola infantum Kyasanur forest disease West Nile fever None 25. Mode of transmission of abdominal TB includes all except Direct spread from mesenteric lymph nodes Hematogenous spread Direct contact with an infected animal Feco-oral route None 26. An HIV patient came to the clinic with a history of diarrhea. Stool microscopy showed the oocysts that were 4-8 µm in size. The image is shown below. Identify the organism. Cryptosporidium Isospora Microspora Cyclospora None 27. Choose the egg belonging to the following parasite. 1 2 3 4 None 28. Which of the following is a gram-positive organism that shows the following appearance on Ziehl-Neelsen staining? Mycobacterium tuberculosis Mycobacterium leprae Actinomyces Nocardia None 29. A patient presents to the hospital with complaints of abdominal pain. A stool examination was done, and it showed the presence of the organism shown in image A. The body has segments broader than the length. Which of the eggs shown in column B corresponds to this organism? 1 2 3 4 None 30. The following are parvovirus-related disease-population pairs. Identify the incorrect pair. Erythema infectiosum - Infants Non-immune hydrops - Pregnant women Non-erosive arthritis - Patients of SLE Aplastic anemia - Patients with hereditary hemolytic anemia 4 3 2 1 None 31. A patient with a history of fever, jaundice, hepatosplenomegaly, and laboratory test result of leptospira IgM reactivity, now presented with breathlessness, fever, and jaundice that worsened after treatment with penicillin. What is the possible diagnosis? Resistant leptospirosis Co-infection with dengue Jarisch-Herxheimer reaction Penicillin allergy None 32. The image below shows the life cycle of a virus. Which of the proteins of the virus act as oncogenes? E6, E7 L1, L2 E1, E2 E1, E2, E5 None 33. On inoculation in the skin, all of the following organisms can lead to dermal, subcutaneous, and lymphatic involvement except Sporothrix schenckii Corynebacterium minutissimum Mycobacterium marinum Nocardia brasiliensis None 34. On Ziehl-Neelsen (ZN) staining oocysts of size 8-10 μm cysts are visible. Identify the organism. Cyclospora Cryptosporidium Isospora Microspora None 35. Image of a Rickettsial morula in a monocyte is shown below. Identify the organism. Rickettsia rickettsii Anaplasma Rickettsia conorii Ehrlichia chaffeensis None 36. Vaccine can be prepared against which of the following proteins of the virus? L1 E6, E7 E1, E2 E3 None 37. The Epstein-Barr virus interacts with B cells via which of the following? CD19 CD20 CD21 CD22 None 38. A young man presents with skin lesions as shown in the image below. All of the following organisms can spread through dermal and subcutaneous lymphatics, except Staphylococcus aureus Mycobacterium marinum Sporothrix schenckii Nocardia asteroides None 39. A forest worker developed skin lesions over the forearm, which initially started as macules but then became nodules. Histology of the nodules shows the following findings. Which of the following is true regarding this condition? These bodies are formed by the engulfment of the dead fungi by the macrophages Angioinvasion is common, especially in people with hemolytic anemia Infection can spread and involve underlying subcutaneous tissue, tendon, muscle or joints It is a dematiaceous fungus None 1 out of 39 Time's up
