Solve Pathology INICET 2020 1. The vacutainer tubes shown in the given image contains: NAF-heparin Trisodium citrate Na-EDTA Clot activator None 2. All of the following are crosslinking fixatives except? Formaldehyde Glutaraldehyde Osmium tetraoxide Methanol None 3. Which of the following is true about celiac disease? Most common cause of malnutrition in developing countries Improves with food rich in carbohydrates Can be diagnosed with CECT Increased risk of Gl lymphoma None 4. All of the following conditions are related to the same core pathology except Parkinson's disease Lewy body dementia Multisystem atrophy Alzheimer's disease None 5. Cells lining the isthmus of the gastric pits Chief cells Parietal cells Stem cells Mucous cells None 6. Isotype switching is seen in Activated B cells Helper T cells B cells Cytotoxic t cells None 7. Which of the following is not true about stem cells? They can differentiate They can replicate They can regenerate damaged tissues They can divide without any regulatory stimulus None 8. Which of the following caspase binds to Cyt c and APAF-1 complex? Caspase 8 Caspase 9 Caspase 1 Caspase 5 None 9. During rounds, you come across the urinalysis report of the 30-year-old male diagnosed with Fabry's disease. What type of urinary casts would you expect to see in the report? RBC cast WBC cast Waxy cast Maltese cross cast None 10. Which of the following is true regarding liquid-based cytology? Sanger sequencing is used DNA is collected in microvessels Study of fluid in tumour microenvironment Urine specimen is used None 11. JAK2 mutation is most commonly associated with CML PMF Polycythemia vera Essential thrombocytosis None 12. A 20-year-old female with easy fatiguability and pallor presented to the OPD. The image of her hand is as given below. What is the most likely diagnosis? Vitamin B12 deficiency Aplastic anemia Hypoalbuminemia Iron deficiency anemia None 13. Which of the following is true regarding glucose-6-phosphate dehydrogenase deficiency? Cells don't lyse in hypotonic solution Cells lyse in hypertonic solution Spectrin defect Cells are spherical None 14. Rees and Ecker diluting fluid is used in RBC Pipette WBC Pipette Wintrobe tube Hemoglobin pipette None 15. The most common lung finding in COVID-19 infection is Pulmonary infarction Fibrin clots Endothelial injury Diffuse alveolar damage None 16. A woman who had undergone total knee replacement surgery comes with complaints of knee pain with the loosening of implants. The following histopathological slide was obtained which showed foreign body giant cells along with the appearance highlighted in the image below. What is your diagnosis? Malignant melanoma Ochronosis Metallosis Rosai dorffman disease None 17. A patient presented to the OPD with long hands and feet, and a protruding lower jaw. Which of the following genes is most likely implicated in this scenario? TPIT GATA1 PIT1 None 18. What is your diagnosis with respect to the findings shown in the peripheral smear given below? Iron deficiency anemia Hereditary spherocytosis B12 deficiency Acute myeloid leukemia None 19. A 24-year-old man met with an RTA and was brought to the casualty after 6 hours. His B.P. was 90/60 mm Hg, heart rate was 110/min, and SpO2 was 92%. A blood transfusion was done. After a few hours, the patient is febrile, tachypneic, and starts bleeding from the IV and NG tube sites. His SpO2 levels started falling. What could be the cause? Acute adrenal crisis Fat embolism Hemorrhagic shock Transfusion reaction None 20. Which of the following is not true about nodular lymphocyte-predominant Hodgkin lymphoma? CD 30 Negative CD 20 positive EBV Negative Poor prognosis compared to classical HL None 21. Which of the following is not a component of Papanicolaou stain? Orange G Eosin B Hematoxylin Light green SF None 22. Which fixation technique is used for fat in the histopathological examination? Formalin-fixed Frozen section Liquid paraffin IHC None 23. Identify the correct statement regarding immune surveillance. Anti-CTLA 4 Ab is a new modality in the treatment of advanced cancers PD1/ PDL1 activation leading to tumor suppression Mutation of tumor suppressor genes decreases antigen toxicity Binding of CD28 leads to immune tolerance None 24. Identify the cells marked in the given image. 1 Â 2 3 4 Lymphocyte-4, Monocyte-3, Eosinophil-1, Basophil-2 Lymphocyte- 1, Monocyte-4, Eosinophil-2, Basophil-3 Lymphocyte-1, Monocyte-2, Eosinophil-3, Basophil-4 Lymphocyte- 4, Monocyte-1, Eosinophil-3, Basophil-2 None 25. Membranoproliferative glomerulonephritis is seen in: HIV CLL SLE Hepatitis B 1, 2 2, 3, 4 1, 2, 3 1, 2, 3, 4 None 26. Which of the following clotting factor deficiency will not affect clotting in vivo? Factor V Factor VII Factor XII Factor IX None 27. Blood examination shows pancytopenia, which can be correct? MDS with hypocellular BM Megaloblastic anemia Hairy cell leukemia APML 1,3,4 1,2,3 2,3,4 1,2 None 28. A child was brought to the emergency department with a big lesion on his forearm. As a surgery resident, you decide to excise the lesion in the emergency operation theatre. Which of the following investigations will test the entire coagulation pathway? Prothrombin time Thromboelastography Activated partial thromboplastin time Bleeding time None 29. The most appropriate biopsy specimen in the case of a thyroid biopsy is? 3 follicular cell clusters contain 10-15 cells 6 follicular cell clusters contain 10-15 cells 10 follicular cell clusters contain 6-8 cells 15 follicular cell clusters contain 10-12 cells None 30. Which of the following conditions will have the least chances of a dry tap on bone marrow aspiration? Follicular Lymphoma AML M7 Myelodysplastic syndrome Hairy Cell Leukemia None Time's up
