Solve Pharmacology AIIMS 2019 1. Clostridium difficile-associated diarrhea occurs maximally due to: Tetracyclines Macrolide Lincosamides Carbapenems None 2. Which of the following causes an increase in ACh release from the presynaptic neuron? Sodium channel blocker Calcium channel blocker Chlorine channel blocker Potassium channel blocker None 3. A 53-year-old man is found to have stage 2 hypertension without any co-morbidities. Which drug will you start? Chlorthalidone Furosemide Spironolactone Triamterene None 4. Apart from mu-opioid receptors, on which other receptor does tramadol act? 5HT1a inhibition Anticholinergic Antihistaminic Serotonergic and norepinephrine reuptake inhibition None 5. Which of the following is a schedule X drug? Thalidomide Colistin Halothane Ketamine None 6. In which of the following conditions is non-pulsatile dosing of GnRH agonist not used? Male infertility Prostate cancer Precocious puberty Endometriosis None 7. LMWH is given by which route? Subcutaneous Intradermal Intramuscular Intravenous None 8. Which of the following cannot be used to decrease intraocular pressure in glaucoma? Dexamethasone Apraclonidine Acetazolamide Mannitol None 9. A patient presents to the emergency department with diarrhea, sweating, excessive lacrimation, and salivation. His pulse rate is 55/min and his plasma cholinesterase level was 50U/mL. Which of the following can be used to treat this patient? Neostigmine Epinephrine Atropine Benztropine None 10. Prucalopride is a 5HT2b agonist 5HT2a agonist 5HT4 agonist 5HT4 antagonist None 11. What is pegloticase used for? Paralytic ileus Rheumatoid arthritis Psoriatic arthritis Chronic gout None 12. Z track technique is used for? Monitoring of carbamazepine therapy Administration of nicotine patches Administration of long-acting depot antipsychotics Monitoring of lithium therapy None 13. Tafenoquine is used in which of the following conditions? Radical cure of plasmodium vivax Treatment of severe falciparum malaria Prophylaxis of malaria in pregnancy Treatment of malaria in children <2 years None 14. Which of the following GPCRs does not act via the K+ channel? Serotonin 5 HT1 receptor Dopamine D2 receptor Angiotensin 1 receptor Muscarinic M2 receptor None 15. Propranolol is drug of choice for: Capillary malformation Pyogenic granuloma Lymphangioma circumscriptum Ulcerated infantile hemangioma None 16. Which is not given in Wilson's disease? Zinc Trientine Penicillamine Calcium citrate None 17. Which of the following is not used in heart failure? Nesiritide Trimetazidine Sacubitril Metoprolol None 18. What dose of epinephrine is used in anaphylactic shock? 1:10000 I.V - 10 ml 1:1000 I.M - 0.5 ml 1:1000 I.V - 0.5 ml 1:1000 I.M - 1 ml None 19. Which of the following is not an adverse effect of salbutamol? Tolerance Tachycardia Hypoglycemia Hypokalemia None 20. Which of the following is true about tedizolid? Poor oral bioavailability Active against gram-positive organisms Active against anaerobes Causes peripheral neuropathy None 1 out of 20 Time's up
