Show session ID Load QuizSave Quiz Solve Pharmacology FMGE 2023 Questions: 23 1. which of the following statements about the given graph is false. a. the efficacy of the drug b and c are equal b. drug A is the most potent drug c. Drug C is less potent and equally efficacious to drug B D. drug D is most efficacious None 2. identify the type of inhibition given in the graph a. competitive b.UN-competitive c.Non-competitive d.allosteric None 3. Which of the following drug acts at the site marked by arrow as shown in the diagram? Blood pressure rises. a. Aliskiren b. Ramipril c. Losartan d.Spironolactone None 4. A new drug is tested in clinical trials and was found to have a therapeutic index of 20. Which of the following statements best describes the therapeutic index of the drug? a. It represents the extent of absorption of the drug and is calculated from the area under curve of the plasma concentration vs time graph b. It represents distribution of the drug in different tissues and is calculated by dividing the plasma concentration with the amount of drug given c. It represents the duration of action of the drug and is calculated from the half life of the drug d. It represents margin of safety of a drug and is calculated as a ratio of TD50 to ED50. None 5. An HIV patient presents with seizures and neck rigidity. The CSF examination shows the presence of organisms on India ink and a diagnosis of cryptococcal meningitis is made. Which of the following anti-fungal drug is used for initial treatment of this meningitis? a. Liposomal amphotericin B . b. High dose fluconazole c. Fluconazole + 5 Flucytosine d. Voriconazole None 6. Which of the following is used for the initial management of the irritative urethral symptoms of benign prostatic hyperplasia? a. Restriction of water intake and wait and watch b. Alpha blocker c. Prostatectomy d. Trans urethral resection of prostate. None 7. Which of the following factors contributes least towards development of mucormycosis? a. Uncontrolled diabetes without ketoacidosis b. Chronic user of antibiotics c. Neutropenia d. Immunosuppression due to steroid therapy None 8. Which of the following statements is most regarding mechanism of action of dicumarol? a. It acts as a calcium chelator and reduces the availability of calcium in coagulation pathway b. It binds and activates anti-thrombin 3 that accelerates its interaction with thrombin and factor Xa resulting in their degradation c. It acts as a Vitamin K inhibitor that results in inhibition of activation of clotting factors 2,7,9 and 10 d. It inhibits tissue plasminogen activator resulting in stoppage of conversion of plasminogen to plasmin None 9. A 5 year old child has taken 10 iron tablets and presents with nausea and abdominal pain. What is the antid of iron poisoning . a. Desferrioxamine b. Penicillamine c. British anti Lewisite. d. EDTA None 10. Which of the following anti-dyslipidemic drug work by stimulating Peroxisome proliferatoractivated receptor( PPAR) alpha . a. Gemfibrozil b. Atorvastatin c. Ezetimibe d. Niacin None 11. A patient is receiving chemotherapy with platinum compounds. Which of the following drugs are used for treatment of chemotherapy induced nausea and vomiting? a.Granisetron, dexamethasone and aprepitant b. Metoclopramide, dexamethasone and domperidone c.Prochlorperazine, granisetron and domperidone d.Promethazine, doxylamine and metoclopramide None 12. A patient of colorectal cancer was treated with folinic acid, 5-fluorouracil and irinotecan therapy. He developed diarrhea following the regimen. Which of the following drug can be used for treatment of chemotherapy related diarrhea in this patient? . a. Atropine b. Loperamide c. Ciprofloxacin d. Metronidazole None 13. A female patient presented with pain and redness in great toe. Serum uric acid level is 9.6 mg/dL. Apart from prescribing analgesics for relieving pain, the physician prescribed a drug which can decrease the formation of uric acid. Which of the following enzyme is likely to be inhibited by this drug? a. Xanthine oxidase synthase b. Thymidylate c. Phosphoribosyl transferase d. DHFR None 14. The given figure shows the effect of a drug on blood pressure and heart rate. The drug is most likely to be a.Epinephrine . b.Nor Epinephrine c.Dopamine d.Isoprenaline None 15. Which of the following correctly describes the phenomenon of vasomotor reversal of Dale? a. Repeated administration of ephedrine decreases its effect on blood pressure b. High dose of acetylcholine after pretreatment with atropine produces increase in blood pressure and heart rate c. A patient pre-treated with phentolamine develops severe hypotension on administration of adrenaline. d. Increase in blood pressure is produced by intravenous propranolol. None 16. A 40 year old male patient presents to hospital with pain in great toe. He was given a medication for one month and the pain subsided. Which of the following drug increases the excretion of uric acid in urine? . a. Colchicine b. Probenecid c. Allopurinol d. Febuxostat None 17. Which of the following statement is correct regarding the mechanism of action of labetalol? adrenergic receptors. a. It blocks both alpha and beta b. It acts as directly acting arterial vasodilator resulting in indirect effect of tachycardia c. It primarily acts as venodilator with little effect on arterioles d. It decreases peripheral vascular resistance by directly acting as relaxant of vascular smooth muscles. None 18. Which of the following drug decreases mortality in a patient with heart failure? a. Furosemide . b. Metoprolol c. Prazosin d. Torsemide None 19. A 22 year old girl presented to hospital with mild fever and night sweats. She was found to have pleural effusion of examination and the adenosine deaminase level in pleural fluid was raised (40 IU/L). Which of the following is the first line antitubercular drug that is used in the treatment regimen for initial two months for this patient? a. Streptomycin b. Ethambutol c. Linezolide d. Levofloxacin None 20. A patient complains of ptosis and increasing muscle weakness by evening. This is relieved by neostigmine. What is the likely diagnosis? a. Myasthenia gravis b. Lambert Eaten syndrome c. Polymyositis d. Multiple sclerosis None 21. Which of the following diuretic acts on the site X shown in the figure? a. Furosemide b. Hydrochlorothiazide c. Spironolactone d. Acetazolamide None 22. Which of the following drug is used to decrease the progression of lung fibrosis and increase exercise cap of a person? a. Roflumilast b. Pirfenidone c. Imatinib d. Bortezomib None 23. A 68 year old male cancer patient on chemotherapy developed neutropenia. Which of the following drug is used to increase the immunity in this person? a. Filgrastim b. Darbopoeitin c. Oprelvekin d. Iron dextran None 1 out of 23 Time's up
